“Humanity is about going beyond biological limitations”

Image: Drawing of The Vitruvian Man

Leonardo da Vinci’s drawing of The Vitruvian man.

NEW YORK Dreams of immortality inspired the fantastical tales of Greek historian Herodotus and Spanish explorer Juan Ponce de Leon’s legendary search for the fountain of youth. Nowadays, visionaries push for the technologies to transplant human brains into new bodies and download human consciousness into hologram-like avatars.

The latest science and schemes for achieving long life and the “singularity” moment of smarter-than-human intelligence came together at the Singularity Summit held here October 15-16. Some researchers explored cutting-edge, serious work about regenerating human body parts and defining the boundaries of consciousness in brain studies. Other speakers pushed visions of extending human existence in “Avatar”- style bodies — one initiative previously backed by action film star Steven Seagal — with fuzzier ideas about how to create such a world.

Above all, the summit buzzed with optimism about technology’s ability to reshape the world to exceed humanity’s wildest dreams, as well as a desire to share that vision with everyone. True believers were even offered the chance to apply for a credit card that transfers purchase rewards to the Singularity Institute.

“Humanity is about going beyond biological limitations,” said Ray Kurzweil, the inventor and futurist whose vision drives the Singularity Institute.

Rebuilding a healthy body The most immediate advances related to living longer and better may come from regenerative medicine. Pioneering physicians have already regrown the tips of people’s fingers and replaced cancer-ridden parts of human bodies with healthy new cells.

“What we’re talking about here is not necessarily increasing the quantity of life but the quality of life,” said Stephen Badylak, deputy director of the McGowan Institute for Regenerative Medicine at the University of Pittsburgh in Pennsylvania.

Success so far has come from using a special connective tissue — called the extracellular matrix (ECM) — to act as a biological scaffold for healthy cells to build upon. Badylak showed a video where his team of surgeons stripped out the cancerous lining of a patient’s esophagus like pulling out a sock, and relined the esophagus with an ECM taken from pigs. The patient remains cancer-free several years after the experimental trial.

The connective tissue of other animals doesn’t provoke a negative response in human bodies, because it lacks the foreign animal cells that would typically provoke the immune system to attack. It has served the same role as a biological foundation for so long that it represents a “medical device that’s gone through hundreds of millions of years of R&D,” Badylak said.

If work goes well, Badylak envisions someday treating stroke patients by regenerating pieces of the functioning human brain.

Live long and prosper The work of such researchers could do more than just keep humans happy and healthy. By tackling end-of-life chronic diseases such as cancer, medical advances could nearly double human life expectancy beyond almost 80 years in the U.S. to 150 years, said Sonia Arrison, a futurist at the Pacific Research Institute in San Francisco, Calif.

Long-lived humans could lead to problems such as anger over a “longevity gap” between haves and have-nots and perhaps add to stress on food, water and energy sources. But Arrison took a more positive view of how “health begets wealth” in a talk based on her new book, “100 Plus” (Basic Books, 2011).

Having healthier people around for longer means that they can remain productive far later in life, Arrison pointed out. Many past innovators accomplished some of their greatest or most creative work relatively late in life — Leonardo da Vinci began painting the Mona Lisa at 51, and Benjamin Franklin conducted his kite experiment at 46.

“Innovation is a late-peak field,” Arrison told the audience gathered at the Singularity Summit.

Even religion might find a renewed role in a world where death increasingly looks far off, Arrison said. Religion remains as popular as ever despite a doubling of human life expectancy up until now, and so Arrison suggested that religions focused on providing purpose or guidance in life could do well. But religions focused on the afterlife may want to rethink their strategy.

Making ‘Avatar’ real (or not) The boldest scheme for immortality came from media mogul Dmitry Itskov, who introduced his “Project Immortality 2045: Russian Experience.” He claimed support from the Russian Federation’s Ministry of Education and Science, as well as actor Seagal, to create a research center capable of giving humans life-extending bodies.

Itskov’s wildly ambitious plans include creating a humanoid avatar body within five to seven years, transplanting a human brain into a new “body B” in 10 to 15 years, digitally uploading a human brain’s consciousness in 20 to 25 years, and moving human consciousness to hologram-like bodies in 30 to 35 years.

That vision may have exceeded even the optimism of many Singularity Summit attendees, given the apparent restlessness of the crowd during Itskov’s presentation. But it did little to dampen the conference’s overall sense that humanity has a positive future within its collective grasp — even if some people still need to be convinced.

“We are storming the fricking barricades of death, both physically and intellectually, so we have to make it sexy,” said Jason Silva, a filmmaker and founding producer/host for Current TV.

By Jeremy Hsu

    10/17/2011 7:39:40 PM ET2011-10-17T23:39:40

You can follow InnovationNewsDaily Senior Writer Jeremy Hsu on Twitter @ScienceHsu. Follow InnovationNewsDaily on Twitter @News_Innovation, or on Facebook.

Scientists Warn of Ethical Battle Concerning Military Mind Control

Scientists Warn of Ethical Battle Concerning Military Mind Control

Advances in neuroscience are closer than ever to becoming a reality, but scientists are warning the military – along with their peers – that with great power comes great responsibility!

March 20, 2012

A future of brain-controlled tanks, automated attack drones and mind-reading interrogation techniques may arrive sooner than later, but advances in neuroscience that will usher in a new era of combat come with tough ethical implications for both the military and scientists responsible for the technology, according to one of the country’s leading bioethicists.

“Everybody agrees that conflict will be changed as new technologies are coming on,” says Jonathan Moreno, author ofMind Wars: Brain Science and the Military in the 21st Century. “But nobody knows where that technology is going.”

[See pictures of Navy SEALs]

Moreno warns in an essay published in the science journal PLoS Biology Tuesday that the military’s interest in neuroscience advancements “generates a tension in its relationship with science.”

“The goals of national security and the goals of science may conflict. The latter employs rigorous standards of validation in the expansion of knowledge, while the former depends on the most promising deployable solutions for the defense of the nation,” he writes.

Much of neuroscience focuses on returning function to people with traumatic brain injuries, he says. Just as Albert Einstein didn’t know his special theory of relativity could one day be used to create a nuclear weapon, neuroscience researchintended to heal could soon be used to harm.

“Neuroscientists may not consider how their work contributes to warfare,” he adds.

Moreno says there is a fine line between using neuroscience devices to allow an injured person to regain baseline functions and enhancing someone’s body to perform better than their natural body ever could.

“Where one draws that line is not obvious, and how one decides to cross that line is not easy. People will say ‘Why would we want to deny warfighters these advantages?'” he says.

[Mind Control, Biometrics Could Change the World]

Moreno isn’t the only one thinking about this. The Brookings Institution’s Peter Singer writes in his book, Wired for War: The Robotics Revolution and Conflict in the 21st Century, that “‘the Pentagon’s real-world record with things like the aboveground testing of atomic bombs, Agent Orange, and Gulf War syndrome certainly doesn’t inspire the greatest confidence among the first generation of soldiers involved [in brain enhancementresearch.]”

The military, scientists and ethicists are increasingly wondering how neuroscience technology changes the battlefield. The staggering possibilities are further along than many think. There is already development on automated drones that are programmed to make their own decisions about who to kill within the rules of war. Other ideas that are closer-than-you-think to becoming a military reality: Tanks controlled from half a world away, memory erasures that could prevent PTSD, and “brain fingerprinting” that could be used to extract secrets from enemies.Moreno foretold some of these developments when he first published Mind Wars in 2006, but not without trepidation.

“I was afraid I’d be dismissed as a paranoid schizophrenic when I first published the book,” he says. But then a funny thing happened—the Department of Defense and other military groups began holding panels on neurotechnology to determine how and when it should be used. I was surprised how quickly the policy questions moved forward. Questions like: ‘Can we use autonomous attack drones?’ ‘Must there be a human being in the vehicle?’ ‘How much of a payload can it have?’. There are real questions coming up in the international legal community.”

All of those questions will have to be answered sooner than later, Moreno says, along with a host of others. Should soldiers have the right to refuse “experimental” brain implants? Will the military want to use some of this technology before science deems it safe?

“There’s a tremendous tension about this,” he says. “There’s a great feeling of responsibility that we push this stuff out so we’re ahead of our adversaries.”

The program is to model machine intelligence on human intelligence by
understanding how our brains work:
Then allow machines to be fully autonomous and enable them to follow their
programming, already machines built from these methods are capable of learning
Why would we want a stupid human factored in to being a pilot? An electrical circuit is
thousands of times faster than protein synapses, why have a worm when you can have an
eagle? Of course we are capable of ‘tele-war’ by connecting nervous systems to devices
tele-tanks are also a possibility.
In the next decade, the program’s timetable is to have functioning real-
life terminators:
Here are other citations you may find interesting:
Functional Magnetic Resonance Imaging (fMRI) and computational models to decode
and reconstruct people’s dynamic visual experiences:
http://www.cell.com/current-biology/abstract/S0960-9822%2811%2900937-7
Data mining opens the door to predictive neuroscience:
http://www.eurekalert.org/pub_releases/2012-04/epfd-dmo041112.php
New drone has no pilot anywhere, so who’s accountable:
http://articles.latimes.com/2012/jan/26/business/la-fi-auto-drone-20120126/2
Artificial synapses could lead to advanced computer memory and machines that
The problem is all of this is old news, the military-industrial complex is 5-10 years
ahead of the public. If I were to say that DARPA is currently working on
smart-dust nanotechnology and is even capable of adding, editing, and
deleting memory in humans would you believe me? Doesn’t matter, time will prove it.

www.opticsinfobase.org

Optics InfoBase is the Optical Society’s online library for flagship journals,
partnered and copublished journals, and recent proceedings from OSA conferences.

How to Use Light to Control the Brain

How to Use Light to Control the Brain

Stephen Dougherty, Scientific American
Date: 01 April 2012 Time: 09:38 AM
 

In the film Amèlie, the main character is a young eccentric woman who attempts to change the lives of those around her for the better. One day Amèlie finds an old rusty tin box of childhood mementos in her apartment, hidden by a boy decades earlier. After tracking down Bretodeau, the owner, she lures him to a phone booth where he discovers the box. Upon opening the box and seeing a few marbles, a sudden flash of vivid images come flooding into his mind. Next thing you know, Bretodeau is transported to a time when he was in the schoolyard scrambling to stuff his pockets with hundreds of marbles while a teacher is yelling at him to hurry up.

We have all experienced this: a seemingly insignificant trigger, a scent, a song, or an old photograph transports us to another time and place. Now a group of neuroscientists have investigated the fascinating question: Can a few neurons trigger a full memory?
In a new study, published in Nature, a group of researchers from MIT showed for the first time that it is possible to activate a memory on demand, by stimulating only a few neurons with light, using a technique known as optogenetics. Optogenetics is a powerful technology that enables researchers to control genetically modified neurons with a brief pulse of light.

To artificially turn on a memory, researchers first set out to identify the neurons that are activated when a mouse is making a new memory. To accomplish this, they focused on a part of the brain called the hippocampus, known for its role in learning and memory, especially for discriminating places. Then they inserted a gene that codes for a light-sensitive protein into hippocampal neurons, enabling them to use light to control the neurons.

With the light-sensitive proteins in place, the researchers gave the mouse a new memory. They put the animal in an environment where it received a mild foot shock, eliciting the normal fear behavior in mice: freezing in place. The mouse learned to associate a particular environment with the shock.

Next, the researchers attempted to answer the big question: Could they artificially activate the fear memory? They directed light on the hippocampus, activating a portion of the neurons involved in the memory, and the animals showed a clear freezing response. Stimulating the neurons appears to have triggered the entire memory.

The researchers performed several key tests to confirm that it was really the original memory recalled. They tested mice with the same light-sensitive protein but without the shock; they tested mice without the light-sensitive protein; and they tested mice in a different environment not associated with fear. None of these tests yielded the freezing response, reinforcing the conclusion that the pulse of light indeed activated the old fear memory.

In 2010, optogenetics was named the scientific Method of the Year by the journal Nature Methods. The technology was introduced in 2004 by a research group at Stanford University led by Karl Deisseroth, a collaborator on this research. The critical advantage that optogenetics provides over traditional neuroscience techniques, like electrical stimulation or chemical agents, is speed and precision. Electrical stimulation and chemicals can only be used to alter neural activity in nonspecific ways and without precise timing. Light stimulation enables control over a small subset of neurons on a millisecond time scale.

Over the last several years, optogenetics has provided powerful insights into the neural underpinnings of brain disorders like depression, Parkinson’s disease, anxiety, and schizophrenia. Now, in the context of memory research, this study shows that it is possible to artificially stimulate a few neurons to activate an old memory, controlling an animals’ behavior without any sensory input. This is significant because it provides a new approach to understand how complex memories are formed in the first place.

Lest ye worry about implanted memories and mind control, this technology is still a long way from reaching any human brains. Nevertheless, the first small steps towards the clinical application of optogenetics have already begun. A group at Brown University, for example, is working on a wireless optical electrode that can deliver light to neurons in the human brain. Who knows, someday, instead of new technology enabling us to erase memories á la Eternal Sunshine of the Spotless Mind, we may actually undergo memory enhancement therapy with a brief session under the lights.

This article was first published on Scientific American. © 2012 ScientificAmerican.com. Follow Scientific American on Twitter @SciAm and @SciamBlogs. VisitScientificAmerican.com for the latest in science, health and technology news.

New Surveillance System Identifies Your Face By Searching Through 36 Million Images Per Second

New Surveillance System Identifies Your Face By Searching Through 36 Million Images Per Second

 

When it comes to surveillance, your face may now be your biggest liability.

Privacy advocates, brace yourselves – the search capabilities of the latest surveillance technology is nightmare fuel. Hitachi Kokusai Electric recently demonstrated the development of a surveillance camera system capable of searching through 36 million images per second to match a person’s face taken from a mobile phone or captured by surveillance. While the minimum resolution required for a match is 40 x 40 pixels, the facial recognition software allows a variance in the position of the person’s head, such that someone can be turned away from the camera horizontally or vertically by 30 degrees and it can still make a match. Furthermore, the software identifies faces in surveillance video as it is recorded, meaning that users can immediately watch before and after recorded footage from the timepoint.

This means that the biggest barrier in video surveillance, which is watching hours of video to find what you want, is gone.

The power of the search capabilities is in the algorithms that group similar faces together. When a search is conducted, results are immediately shown as thumbnails, and selecting a thumbnail pulls up the stored footage for review. Because the search results are displayed as a grid, mistaken identifications can be ruled out quickly or verified by pulling up the entire video for more information.

The scenarios that this system could be useful for are endless. The police, for instance, could find individuals from old surveillance video or pick them out of large crowds, whether they are suspects or people who’ve been kidnapped. Or if a retail customer is caught stealing something on camera, the system could pull up footage from each time the customer has been in the store to identify other thefts that went unnoticed.

Rapid search of the video database allows users to review video around key timepoints.

The company, which specializes in video cameras for the imaging, medical, and security markets, states that the system is ideally suited for large-scale customers, such as law enforcement agencies, transportation centers, and retail centers. The system will be released in the next fiscal year presumably customized to specific customer’s needs. Interested parties have to contact the company directly, which is probably wise in order to control whose hands it ends up in. And this means that soon, the only thing that’s going to be anonymous anymore are the agencies and organizations using the software.

While this news should make anyone concerned about privacy shudder, it really was only a matter of time before something like this was developed. Likewise, it means that competing systems will follow until systems like this are common. So it will be up to legislators to define how the technology can be used legally as with other surveillance systems, like license-plate recognition cameras.

Check out the video from the security trade show so you can see for yourself just how easy it is to be Big Brother with this system:

[Media: YouTube]

[Sources: DigInfoDigital TrendsPhysOrg]